Identification
Name:Poly-beta-1,6-N-acetyl-D-glucosamine export protein
Synonyms:Not Available
Gene Name:pgaA
Enzyme Class:Not Available
Biological Properties
General Function:transport
Specific Function:Exports the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PGA) across the outer membrane. The PGA transported seems to be partially N-deacetylated since N-deacetylation of PGA by PgaB is needed for PGA export through the PgaA porin.Required for the synthesis of the beta-1,6-GlcNAc polysaccharide (PGA or poly-GlcNAc) that seems to serve as a biofilm adhesin.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell outer membrane
integral component of membrane
substrate-specific transmembrane transporter activity
transmembrane transport
transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>2424
atgtattcaagtagcagaaaaaggtgcccgaaaaccaaatgggctttgaaacttcttact
gccgcatttttagcagcgagtcccgcggcgaagagtgctgttaataacgcctatgatgca
ttgattattgaagctcgcaagggtaatactcagccagctttgtcatggtttgcactaaaa
tcagcactcagcaataaccaaattgctgactggttacagattgccttatgggccgggcaa
gataaacaggttattaccgtttacaaccgctaccgtcatcagcaattaccagcgcgtggt
tatgcagctgtcgccgtcgcttatcgtaacctgcaacaatggcaaaactcgcttacactg
tggcaaaaggcgctctctctggagccgcaaaataaggattatcaacggggacaaatttta
accctggcagatgctggtcactatgatactgcgctggttaaacttaagcagcttaactct
ggagcaccggacaaagccaatttactcgcagaagcctatatctataaactggcggggcgt
catcaggatgaattacgggcgatgacagagtcattacctgaaaatgcatctacgcaacaa
tatcccacagaatacgtgcaggcattacgtaataatcaacttgctgccgcgattgacgat
gccaatttaacgccagatattcgcgctgatattcatgccgaactggtcagactgtcgttt
atgcctacgcgcagtgaaagtgaacgttatgccattgccgatcgcgccctcgcccaatac
gctgcattagaaattctgtggcacgataacccagaccgcactgcccagtaccagcgtatt
caggttgatcatcttggcgcgttattaactcgcgatcgttataaagacgttatttctcac
tatcagcgattaaaaaagacggggcaaattattccgccctgggggcaatattgggttgca
tcggcttatctcaaagatcatcagccgaaaaaagcacagtcaataatgaccgagctcttt
tatcacaaggagaccattgccccggatttatccgatgaagaacttgcggatctcttttac
agccacctggagagtgaaaattatccgggcgcgctaactgtcacccaacataccattaat
acttcgccgcctttccttcggttaatgggcacgcctacgagcatcccgaatgatacctgg
ttacaggggcattcgtttctctcaaccgtagcaaaatatagtaatgatcttcctcaggct
gaaatgacagccagagagcttgcttataacgcaccaggaaatcagggactgcgcattgat
tacgcgagtgtgttacaagcccgcggttggcctcgtgcagcagaaaatgaattaaaaaaa
gcagaagtgatcgagccacgtaatattaatctggaggttgaacaagcctggacagcatta
acgttacaagaatggcagcaggcagctgtcttaacgcacgatgttgtcgaacgtgaaccg
caagatcccggcgttgtacgattaaaacgtgcggttgatgtacataatcttgcagagctt
cgtatcgctggctcaacaggaattgatgccgaaggcccggatagtggtaaacatgatgtc
gacttaaccaccatcgtttattcaccaccgctgaaggataactggcgcggttttgctgga
ttcggttatgccgatggacaatttagcgaaggaaaagggattgttcgcgactggcttgcg
ggtgttgagtggcggtcacgtaatatctggctcgaggcagagtacgctgaacgcgttttc
aatcatgagcataaacccggcgcgcgcctgtctggctggtatgattttaatgataactgg
cgtattggttcgcaactggaacgcctctctcaccgcgttccattacgggcaatgaaaaat
ggtgttacaggcaacagtgctcaggcttatgttcgctggtatcaaaatgagcggcgtaag
tacggtgtctcctgggctttcactgatttttccgacagtaaccagcgtcatgaagtctca
cttgagggtcaggaacgcatctggtcttcaccatatttgattgtcgatttcctacccagt
ctgtattacgaacaaaatacagaacacgataccccatactacaaccctataaaaacgttc
gatattgttccggcatttgaggcaagccatttgttatggcgaagctatgaaaatagctgg
gagcaaatattcagcgcaggtgttggtgcctcctggcaaaaacattatggcacggatgtc
gtcacccaactcggctacgggcaacgcattagttggaatgacgtgattgatgctggcgca
acgctacgctgggaaaaacgaccttatgacggtgacagagaacacaacttatacgttgaa
ttcgatatgacattcagattttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:807
Protein Molecular Weight:92206
Protein Theoretical pI:Not Available
Signaling Regions:
  • 1-26
Transmembrane Regions:Not Available
Protein Sequence:
>Poly-beta-1,6-N-acetyl-D-glucosamine export protein
MYSSSRKRCPKTKWALKLLTAAFLAASPAAKSAVNNAYDALIIEARKGNTQPALSWFALK
SALSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYAAVAVAYRNLQQWQNSLTL
WQKALSLEPQNKDYQRGQILTLADAGHYDTALVKLKQLNSGAPDKANLLAEAYIYKLAGR
HQDELRAMTESLPENASTQQYPTEYVQALRNNQLAAAIDDANLTPDIRADIHAELVRLSF
MPTRSESERYAIADRALAQYAALEILWHDNPDRTAQYQRIQVDHLGALLTRDRYKDVISH
YQRLKKTGQIIPPWGQYWVASAYLKDHQPKKAQSIMTELFYHKETIAPDLSDEELADLFY
SHLESENYPGALTVTQHTINTSPPFLRLMGTPTSIPNDTWLQGHSFLSTVAKYSNDLPQA
EMTARELAYNAPGNQGLRIDYASVLQARGWPRAAENELKKAEVIEPRNINLEVEQAWTAL
TLQEWQQAAVLTHDVVEREPQDPGVVRLKRAVDVHNLAELRIAGSTGIDAEGPDSGKHDV
DLTTIVYSPPLKDNWRGFAGFGYADGQFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVF
NHEHKPGARLSGWYDFNDNWRIGSQLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRK
YGVSWAFTDFSDSNQRHEVSLEGQERIWSSPYLIVDFLPSLYYEQNTEHDTPYYNPIKTF
DIVPAFEASHLLWRSYENSWEQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGA
TLRWEKRPYDGDREHNLYVEFDMTFRF
References
External Links:
ResourceLink
Uniprot ID:P69434
Uniprot Name:PGAA_ECOLI
CCDB:PGAA_ECOLI
General Reference:Not Available