Identification
Name:Protein Sxy
Synonyms:Not Available
Gene Name:sxy
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy-activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP (PubMed:17068078, PubMed:22532864). Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs (PubMed:19502395).
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
DNA import into cell involved in transformation
establishment of competence for transformation
positive regulation of type IV pilus biogenesis
regulation of sequence-specific DNA binding transcription factor activity
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>630
atgaaaagcctctcctataagcggatctataaatcacaagaatacctggcaacgttgggc
acaattgaataccgatcattgtttggcagttacagcctgaccgttgacgacacggtgttt
gcgatggtttctgatggtgagttgtatcttcgggcttgtgagcaaagtgcacagtactgt
gtaaaacatccgcctgtctggctgacatataaaaagtgtggccgatccgttaccctcaat
tactatcgggttgatgaaagtctatggcgaaatcaactgaagctggtgcgtctgtcgaaa
tattctctcgatgcagcgctgaaagagaaaagcacgcgcaatacccgggaaagactgaaa
gatttgcccaatatgtcttttcatctggaagcgattctcggggaggtggggattaaggat
gtacgggcgttacgtatacttggggcaaaaatgtgttggttgcgactgcggcagcaaaac
agtctggtgacagaaaagattctgtttatgcttgaaggtgccattatcggcattcatgaa
gctgcgctcccggtggcacgccgccaggagcttgcagaatgggctgactctcttacgccg
aaacaggagtttcctgcggaacttgagtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:209
Protein Molecular Weight:24146
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Protein Sxy
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYC
VKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLK
DLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQNSLVTEKILFMLEGAIIGIHE
AALPVARRQELAEWADSLTPKQEFPAELE
References
External Links:
ResourceLink
Uniprot ID:P75869
Uniprot Name:SXY_ECOLI
CCDB:SXY_ECOLI
General Reference:Not Available