Identification
Name:Anti-adapter protein IraM
Synonyms:Not Available
Gene Name:iraM
Enzyme Class:Not Available
Biological Properties
General Function:positive regulation of transcription, DNA-templated
Specific Function:Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation. May also be involved in the early steps of isoprenoid biosynthesis, possibly through its role as RssB regulator.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
anti-sigma factor antagonist activity
cellular response to acidic pH
cellular response to magnesium starvation
cytoplasm
negative regulation of protein catabolic process
positive regulation of transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>324
atgaagtggatagtaattgacacggtaattcaacctacatgtggtatatctttttcagcc
atatggggtaatatgaaaatgatcatctggtatcaatctactatatttctccctcctggc
agtatatttacaccggttaagtctggtattatccttaaggataaagaatatcctattact
atttatcacatcgcaccattcaacaaggatttatggagtttactcaaaagcagtcaagag
tgtcctccaggagaaagcaaaataacaaataaatgtttacataatagttgcattataaaa
atatgcccatatgggctcaagtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:107
Protein Molecular Weight:12133
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Anti-adapter protein IraM
MKWIVIDTVIQPTCGISFSAIWGNMKMIIWYQSTIFLPPGSIFTPVKSGIILKDKEYPIT
IYHIAPFNKDLWSLLKSSQECPPGESKITNKCLHNSCIIKICPYGLK
References
External Links:
ResourceLink
Uniprot ID:P75987
Uniprot Name:IRAM_ECOLI
CCDB:IRAM_ECOLI
General Reference:Not Available