Identification
Name:HTH-type transcriptional regulator DmlR
Synonyms:Not Available
Gene Name:dmlR
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Transcriptional regulator required for the aerobic growth on D-malate as the sole carbon source. Induces the expression of dmlA in response to D-malate or L- or meso-tartrate. Negatively regulates its own expression.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
DNA binding
malate metabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>924
atgaataatttaccgctgctgaatgatttgcgcgtctttatgctggtggctcgccgggct
ggttttgccgccgtggcggaagaactgggcgtttcaccggcgttcgtcagcaagcgcatc
gccttgctggagcaaacgctaaacgtggtgttgttacaccgcaccacccgccgcgtcacc
attaccgaagaaggagagcggatttatgaatgggcgcagcggattttgcaggatgtcggt
cagatgatggacgaactttctgacgtgcgtcaggtgccgcaggggatgctgcgtattatc
agcagctttggttttggacgacaggtggtggctccggcgttattagcgctggcgaaggcg
tatccgcaactggaattacgttttgatgtggaagaccgactggtcgatttggtcaatgaa
ggtgtcgatctcgatattcgcattggcgatgacatcgcccctaatttaatcgcccgcaaa
ctggcgaccaattaccgtattctctgcgcgtcgccggaatttattgcgcaacatggcgcg
ccgaaacatttaaccgatctttctgcattgccgtgcctggtcattaaagagcgcgatcat
ccttttggtgtctggcaattacgcaataaagaaggcccccatgcgattaaagtcaccggc
ccactgtcgtctaatcatggagaaattgtccatcagtggtgtctcgatgggcaggggatt
gctctgcgttcctggtgggatgttagcgaaaacattgccagtggtcatttagtgcaagtg
ctaccggaatattaccagccagcgaacgtctgggccgtttatgtttcaaggctggcgacg
tcagcgaaagtgcggataacggtagaatttttacgccagtattttgccgagcactacccg
aatttttcactggagcatgcctga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:307
Protein Molecular Weight:34630
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>HTH-type transcriptional regulator DmlR
MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVT
ITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALLALAKA
YPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGA
PKHLTDLSALPCLVIKERDHPFGVWQLRNKEGPHAIKVTGPLSSNHGEIVHQWCLDGQGI
ALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVSRLATSAKVRITVEFLRQYFAEHYP
NFSLEHA
References
External Links:
ResourceLink
Uniprot ID:P76250
Uniprot Name:DMLR_ECOLI
CCDB:DMLR_ECOLI
General Reference:Not Available