| Identification |
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| Name: | tRNA (cmo5U34)-methyltransferase |
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| Synonyms: | Not Available |
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| Gene Name: | cmoA |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | tRNA wobble uridine modification |
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| Specific Function: | Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U). |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| methylation | | S-adenosylmethionine-dependent methyltransferase activity | | tRNA (uracil) methyltransferase activity | | tRNA wobble uridine modification |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >744
atgtctcaccgcgacacgctattttctgcccctatcgccagactgggcgactggaccttt
gatgaacgggtagctgaagtcttcccggatatgatccagcgttccgtacccggctattcc
aatattatttccatgattggtatgttagccgagcgcttcgttcaacctggtacgcaggtt
tacgatctgggttgttctctgggcgcggcgacgctctcggtgcgtcgcaacattcatcat
gataattgcaaaattattgccatcgacaactccccggcgatgattgaacgctgccgtcgt
catattgacgcctataaagcccctacgccagtagacgtcattgaaggtgatattcgcgat
atcgccattgaaaacgcatcgatggtggtgctgaattttaccctgcaattcctggaacct
tccgagcgccaggcgttactggataaaatttatcaagggctgaaccccggcggcgcgctg
gtgctttcggaaaaattcagtttcgaagatgccaaagttggtgaactgttgttcaacatg
caccacgactttaaacgtgccaacggttacagcgaactggagatcagccagaagcgcagc
atgctggaaaacgtgatgctgaccgattccgtggaaacccataaagcacgcctgcataac
gccggttttgagcatagtgagctgtggttccagtgctttaactttggttcactggtggca
ttaaaagcagaggacgctgcatga |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 247 |
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| Protein Molecular Weight: | 27776 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 4IWN |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >tRNA (cmo5U34)-methyltransferase
MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQV
YDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRD
IAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNM
HHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHNAGFEHSELWFQCFNFGSLVA
LKAEDAA |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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