Identification
Name:Long-chain acyl-CoA thioesterase FadM
Synonyms:
  • Acyl-CoA thioester hydrolase
  • Thioesterase 3
Gene Name:fadM
Enzyme Class:Not Available
Biological Properties
General Function:Not Available
Specific Function:Long-chain acyl-CoA thioesterase with a preference for 3,5-tetradecadienoyl-CoA. Could be involved in beta-oxidation of fatty acids. Long-chain acyl-CoA thioesterase with a preference for 3,5-tetradecadienoyl-CoA. Could be involved in beta-oxidation of fatty acids.
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
ECMDB203603,5-Tetradecadienoyl-CoAMetaboCard
ECMDB01423Coenzyme AMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b0443
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>ENA|AAC73546|AAC73546.1 Escherichia coli str. K-12 substr. MG1655 long-chain acyl-CoA thioesterase III
ATGCAAACACAAATCAAAGTTCGTGGATATCATCTCGACGTTTACCAGCACGTCAACAAC
GCCCGCTACCTTGAATTTCTCGAAGAAGCCCGCTGGGATGGGTTGGAAAATAGCGACAGT
TTTCAGTGGATGACGGCCCATAACATCGCCTTCGTCGTGGTCAATATCAATATTAACTAT
CGTCGCCCAGCGGTATTAAGTGACCTGTTAACTATTACCAGTCAGTTGCAGCAATTAAAC
GGTAAAAGCGGCATCTTAAGCCAGGTCATTACACTGGAGCCGGAAGGGCAGGTGGTAGCG
GATGCGCTTATTACGTTTGTTTGTATTGATCTTAAAACGCAGAAAGCATTAGCTCTGGAA
GGGGAATTGCGCGAAAAGCTGGAGCAGATGGTTAAGTAA
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:Not Available
Protein Molecular Weight:Not Available
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>sp|P77712|FADM_ECOLI Long-chain acyl-CoA thioesterase FadM OS=Escherichia coli (strain K12) GN=fadM PE=1 SV=1
MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFQWMTAHNIAFVVVNININY
RRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADALITFVCIDLKTQKALALE
GELREKLEQMVK
References
External Links:
ResourceLink
Uniprot ID:P77712
ColiBase:b0443
Kegg Gene:b0443
BacMap:16128428
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Feng, Y., Cronan, J. E. (2009). "A new member of the Escherichia coli fad regulon: transcriptional regulation of fadM (ybaW)." J Bacteriol 191:6320-6328. Pubmed: 19684132
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Nie, L., Ren, Y., Schulz, H. (2008). "Identification and characterization of Escherichia coli thioesterase III that functions in fatty acid beta-oxidation." Biochemistry 47:7744-7751. Pubmed: 18576672