Toxin CptA (Q46824)

Identification
Name:Toxin CptA
Synonyms:Not Available
Gene Name:cptA
Enzyme Class:Not Available
Biological Properties
General Function:regulation of cell shape
Specific Function:Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB; inhibits FtsZ GTP-dependent polymerization as well as MreB ATP-dependent polymerization.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
integral component of plasma membrane
negative regulation of protein binding
regulation of cell shape
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>408
gtggtcctgtggcaatctgatttgcgcgtctcctggcgcgcacagtggctttccttgctg
attcatgggctggttgccgctgttattttactcatgccctggccactcagttacaccccg
ttatggatggtgttactttcgctggtggtgtttgattgcgttcgcagccagcggcgtatt
aatgctcgccagggggaaattcgcttgttgatggacgggcgtttgcgttggcaagggcag
gagtggagcatcgtcaaagcaccgtggatgattaagagcggcatgatgctgcgtttacgt
tctgatggcggtaaacggcaacatttatggctggcagccgacagcatggacgaagctgaa
tggcgggatttacggcggattttgttgcaacaagagacgcaaagataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:135
Protein Molecular Weight:16063
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 12-32
  • 38-54
Protein Sequence:
>Toxin CptA
MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLMPWPLSYTPLWMVLLSLVVFDCVRSQRRI
NARQGEIRLLMDGRLRWQGQEWSIVKAPWMIKSGMMLRLRSDGGKRQHLWLAADSMDEAE
WRDLRRILLQQETQR
References
External Links:
ResourceLink
Uniprot ID:Q46824
Uniprot Name:CPTA_ECOLI
CCDB:CPTA_ECOLI
General Reference:Not Available