ECMDB: Antitoxin DinJ (Q47150)

Identification

Name:

Antitoxin DinJ

Synonyms:

Not Available

Gene Name:

dinJ

Enzyme Class:

Not Available

Biological Properties

General Function:

transcription, DNA-templated

Specific Function:

Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin that counteracts the effect of the YafQ toxin. YafQ and DinJ together bind their own promoter, and by analogy to other TA modules probably repress its expression.Cell death governed by the MazE-MazF and DinJ-YafQ TA modules seems to play a role in biofilm formation.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding
negative regulation of DNA-templated transcription, initiation
single-species biofilm formation
toxic substance binding
transcription, DNA-templated

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>261
atggctgctaacgcgtttgttcgcgcccgaatcgatgaagatctgaagaatcaggcagcg
gacgtactggccgggatggggctgaccatctctgacctggttcgcataaccctcacaaag
gtcgcgcgtgaaaaggcattgccgtttgatttacgcgagcctaatcaattaaccattcaa
tcaatcaaaaacagcgaagctggcattgatgttcataaggccaaagacgccgatgattta
tttgataaattaggaatttaa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

Protein Molecular Weight:

9405

Protein Theoretical pI:

Not Available

PDB File:

4Q2U

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Antitoxin DinJ
MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVAREKALPFDLREPNQLTIQ
SIKNSEAGIDVHKAKDADDLFDKLGI

References

External Links:

Resource	Link
Uniprot ID:	Q47150
Uniprot Name:	DINJ_ECOLI
PDB ID:	4Q2U
CCDB:	DINJ_ECOLI

General Reference:

Not Available